Peter Kay’s connection to severe disease – what is it and what are the symptoms?

Any major organs and systems can be affected including the brain, heart, lungs, gut, liver and skin.

There are some recognisable mitochondrial syndromes that have specific patterns and experts have been able to name them.

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One that is part of a larger group of conditions known as mitochondrial DNA depletion disorders is Alpers’ syndrome.

This is caused by mistakes in the DNA of a gene known as POLG and can cause severe epilepsy, a loss of developmental skills and liver failure.

Source: Daily Express