Melatonin is a hormone that is produced in the brain. It regulates the body’s circadian rhythm, hormones secreted by the endocrine system, and sleep patterns.

Experts may recommend a melatonin supplement for certain conditions like jet lag or insomnia, but those supplements are synthetically made in a laboratory. (For natural sleep-supporting supplements, check out these 5 Absolute Best Foods to Eat For Better Sleep.) Usually, the supplements come in pill form, but they can also be found in a form that you place in the cheek or under your tongue so it gets absorbed quickly into the body.

If you’re looking to take melatonin, here are 5 side effects that you may experience.

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Some folks have trouble falling asleep at a usual bedtime. Research shows that taking melatonin supplements can help reduce the length of time young adults and kids fall asleep (in those who have trouble falling asleep). It should be noted that this supplement is not regulated by the Food and Drug Administration (FDA) and should only be used in children and adults after speaking with a medical doctor.

Woman using a laptop at home stops, her hand to her head.Woman using a laptop at home stops, her hand to her head.
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If you take melatonin during the day, it can cause sleepiness. This is why when you take it matters. It is advised not to drive or use machinery for 4 to 5 hours after taking the supplement.

Middle aged woman suffering from abdominal pain while sitting on bed at homeMiddle aged woman suffering from abdominal pain while sitting on bed at home
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When taken orally, melatonin has been reported to have side effects like nausea, abdominal cramps, mild abdominal pain, diarrhea, decreased appetite, and/or constipation. Oftentimes these symptoms happen within the first few days of taking the supplement and then subside after a few days.

READ MOREThe Best Supplements for Digestion, According to Dietitians

Man sitting on bed holding his head.Man sitting on bed holding his head.
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When taken orally, melatonin has been reported to cause migraine-like headaches or dizziness, especially during the first few days. The symptoms tend to be more common when melatonin is taken in the morning or at high doses (greater than 50mg).

happy young woman in bed with white sheets stretching in front of windows in morninghappy young woman in bed with white sheets stretching in front of windows in morning
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Taking 2 to 3 milligrams of melatonin daily when traveling to a different time zone seems to improve alertness and reduce daytime sleepiness in those with jet lag. There is also some evidence that melatonin supplements may help improve other jet lag symptoms including fatigue.

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Toby Amidor, MS, RD, CDN

Toby Amidor is an award winning dietitian and Wall Street Journal best-selling cookbook author who believes healthy and wholesome can also be appetizing and delicious. Read more

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